My advice is that it depends. If you live in a city that has a demand for photos, and you are going to concentrate on photos of the that city, then I would say yes. If you are going to upload all sorts of images then it might not be such a good idea.
If I’m looking for “apples” I’d probably skip http://www.cityphotos.com and search else where. Remember that your photos will be indexed on the net by their names and keywords.
If you are an all around photographer I would brand yourself first and foremost, then you can be known to take photos of your city. Does that make sense?
Anyway, there is no exact science to any of this. These are just my opinions.